منابع مشابه
Computational Neurogenetic Modeling: Gene-Dependent Dynamics of Cortex and Idiopathic Epilepsy
The chapter describes a novel computational approach to modeling the cortex dynamics that integrates gene–protein regulatory networks with a neural network model. Interaction of genes and proteins in neurons affects the dynamics of the whole neural network. We have adopted an exploratory approach of investigating many randomly generated gene regulatory matrices out of which we kept those that g...
متن کاملComputational Modeling
| A computational modeling system (CMS) provides scientiic investigators with a uni-ed computational environment and easy access to a broad range of modeling tools. The goal of a CMS is to provide computational support that increases the eeciency of scientists in the iterative process of modeling. A CMS consists of a computational modeling environment and transparent computational support for t...
متن کاملNeurogenetic Adaptive Mechanisms
Clinical, genetic, and neuropsychopharmacological studies ofdevelopmental factors in alcoholism are providing a better understanding of the neurobiological bases of personality and learning. Studies of the adopted-away children of alcoholics show that the predisposition to initiate alcohol-seeking behavior is geneticaily different from susceptibility to loss of control after drinking begins. Al...
متن کاملRunning a neurogenetic clinic.
The explosion of molecular genetic information over the last 10 years has resulted in a large number of genes being discovered for single gene disorders. Since the majority of the thousands of genes expressed in humans are in the nervous system (central and peripheral nervous systems), it is perhaps unsurprising that mutations in many of the discovered genes cause neurological disease. At prese...
متن کاملComputational Neurogenetic Modelling: a Pathway to New Discoveries in Genetic Neuroscience
The paper presents a methodology for using computational neurogenetic modelling (CNGM) to bring new original insights into how genes influence the dynamics of brain neural networks. CNGM is a novel computational approach to brain neural network modelling that integrates dynamic gene networks with artificial neural network model (ANN). Interaction of genes in neurons affects the dynamics of the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2008
ISSN: 1601-1848,1601-183X
DOI: 10.1111/j.1601-183x.2008.00424_5.x